As part of the development of its One Stop Shop for research ethics and governance, the Australian Commission on Safety and Quality in Health Care consulted on the minimum requirements for nationally consistent Site-Specific Assessment (SSA. Australian Genomics was represented at workshops where the proof-of-concept submission platform was demonstrates, as well as providing a written response to the consultation. The experience of Australian Genomics research coordinators with navigating different SSA requirements and submission portals informed the response.